All-Grass of Chinese Fevervine
- Chinese
- 鸡矢藤
- Pinyin
- Ji Shi Teng
- Latin
- Herba Paederiae
Known in TCM as Ji Shi Teng (鸡矢藤), this sweet and sour, neutral herb enters the Liver, Heart, Spleen, and Kidney. Traditionally, it dispels wind and eliminates dampness, most often applied for rheumatoid arthritis, dyspepsia, and dysentery. Modern research has identified Iridoid glycosides (paederoside, scandoside, asperulosidic acid) among its active constituents.
Part used: Whole herb
Also Known As
Latin: Herba Paederiae | Pinyin: Ji Shi Teng | Chinese: 鸡矢藤
TCM Properties
- Taste
- sweet, sour
- Temperature
- neutral
- Channels
- Liver, Heart, Spleen, Kidney
Traditional Use
Primary Actions
- Dispels wind and eliminates dampness … used for rheumatic joint pain, numbness, and bi-syndrome from wind-damp obstruction
- Promotes digestion and resolves food stagnation … used for childhood malnutrition, dyspepsia, diarrhea, and abdominal pain from food accumulation
- Removes toxicity and reduces swelling … used for dysentery, jaundice, skin infections, and toxic swellings
Secondary Actions
- Activates blood circulation and alleviates pain … used for traumatic pain, headache, and abdominal pain from blood stasis
- Antitussive and antidiarrheal … addresses cough and diarrhea as secondary applications
Modern Research
Active Compounds
- Iridoid glycosides (paederoside, scandoside, asperulosidic acid) … primary bioactive constituents; analgesic, anti-inflammatory, and neuroprotective
- Flavonoids … antioxidant and anti-inflammatory secondary metabolites
- Volatile oils … contribute to the characteristic sulfur-containing odor; include paederoside thioether
- Triterpenoids and alkaloids … additional bioactive constituents with multiple pharmacological activities
Studied Effects
- Anti-inflammatory … iridoid glycosides inhibit NF-κB, COX-2, iNOS, IL-1β, and IL-6; IC50 of 15.30 μM for NO inhibition (PMID 37172671)
- Analgesic … aqueous fraction (iridoid + polysaccharide-rich) produces significant antinociception in acetic acid, formalin, tail-flick, and hot-plate pain models in mice (PMID 25115105)
- Anti-inflammatory and immunomodulatory on uric acid nephropathy … iridoid glycoside fraction reduces renal inflammation in animal models (PMID 22910180)
PubMed References
- Anti-inflammatory iridoid glycosides from Paederia scandens (Lour.) Merrill (2023)
- A phytochemical, pharmacological and clinical profile of Paederia foetida and P. scandens (2014)
- Anti-inflammatory and immunomodulatory effects of iridoid glycosides from Paederia scandens on uric acid nephropathy rats (2012)
Safety & Interactions
Cautions
- Strong sulfurous odor when crushed … handle in well-ventilated areas
- MSK page not found … drug interaction data not available from Memorial Sloan Kettering integrative medicine database
Conditions
Frequently Asked Questions
What is All-Grass of Chinese Fevervine used for?
All-Grass of Chinese Fevervine is traditionally used to Dispels wind and eliminates dampness … used for rheumatic joint pain, numbness, and bi-syndrome from wind-damp obstruction, Promotes digestion and resolves food stagnation … used for childhood malnutrition, dyspepsia, diarrhea, and abdominal pain from food accumulation, Removes toxicity and reduces swelling … used for dysentery, jaundice, skin infections, and toxic swellings. Research has investigated its effects on: Anti-inflammatory … iridoid glycosides inhibit NF-κB, COX-2, iNOS, IL-1β, and IL-6; IC50 of 15.30 μM for NO inhibition (PMID 37172671); Analgesic … aqueous fraction (iridoid + polysaccharide-rich) produces significant antinociception in acetic acid, formalin, tail-flick, and hot-plate pain models in mice (PMID 25115105).
What are other names for All-Grass of Chinese Fevervine?
All-Grass of Chinese Fevervine is also known as Paederia. In TCM: 鸡矢藤 (Ji Shi Teng); Herba Paederiae.
Is All-Grass of Chinese Fevervine safe during pregnancy?
The safety of All-Grass of Chinese Fevervine during pregnancy has not been established. Consult a qualified healthcare provider before use.