Asiatic Pennywort Herb

Chinese
积雪草
Pinyin
Ji Xue Cao
Latin
Herba Centellae
Botanical illustration of Asiatic Pennywort Herb, Centella asiatica, showing creeping whole-herb habit, rounded leaves, rooted nodes, umbels, and diagnostic plant details.
Botanical plate by Kodi . View print →

Known in TCM as Ji Xue Cao (积雪草), this bitter and acrid, cold herb enters the Liver, Spleen, and Kidney. Traditionally, it clears Heat and promotes urination, most often applied for jaundice, urinary tract infection, and eczema. Modern research has identified Asiaticoside among its active constituents.

Part used: Whole herb

Also Known As

Centella

Latin: Herba Centellae | Pinyin: Ji Xue Cao | Chinese: 积雪草

TCM Properties

Taste
bitter, acrid
Temperature
cold
Channels
Liver, Spleen, Kidney

Traditional Use

Primary Actions

  • Clears Heat and promotes urination … used for Damp-Heat jaundice, painful urinary disorders, and summer-heat dysentery
  • Resolves toxicity and reduces swelling … applied internally or topically for abscesses, sores, shingles, and inflamed skin lesions
  • Promotes tissue regeneration and wound healing … valued for traumatic injury, chronic sores, burns, and delayed healing
  • Cools Blood and stops bleeding while also invigorating Blood … used for blood in the urine, epistaxis, bruising, and traumatic swelling

Secondary Actions

  • Supports the Liver and Gallbladder in Damp-Heat patterns with jaundice or hepatitis
  • Fresh herb juice or poultice is a classic folk application for red eyes, sore throat, and hot swellings

Classical References

  • Shen Nong Ben Cao Jing (Divine Husbandman's Classic of Materia Medica) … records Ji Xue Cao as bitter and cold, indicated for great Heat, malignant sores, abscesses, spreading sores, red skin lesions, and fever.
  • Xin Xiu Ben Cao (Tang dynasty) … describes the coin-shaped leaves and recommends the pounded fresh herb applied topically for hot swellings and erysipelas.
  • Ben Cao Gang Mu (Compendium of Materia Medica, Li Shizhen, 1578) … notes that the expressed juice can be used for sudden red eyes and other acute Heat conditions.

Modern Research

Active Compounds

  • Asiaticoside
  • Madecassoside
  • Asiatic acid
  • Madecassic acid
  • Flavonoids and polyphenols

Studied Effects

  • Wound-healing and collagen support … asiaticoside increased collagen content, tensile strength, and epithelization in normal and delayed wound-healing models (PMID 10350364)
  • Chronic venous insufficiency support … systematic review found improvement in microcirculatory parameters, edema, and related symptoms in controlled trials (PMID 23533507)
  • Dermatologic scar and burn support … review literature highlights triterpenes for small wounds, hypertrophic scars, and burns (PMID 24399761)

PubMed References

Safety & Interactions

Contraindications

  • Spleen and Stomach deficiency-cold with loose stools or poor appetite
  • Cold-pattern dysmenorrhea or menstruation with marked Cold signs

Cautions

  • High doses or prolonged use may cause digestive upset or contribute to liver irritation in susceptible patients
  • Use with caution in patients with existing liver disease or when combining with other potentially hepatotoxic supplements

Drug Interactions

  • CYP450 substrate drugs … In vitro gotu kola inhibits CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 and may alter intracellular concentrations of substrate drugs (Moderate) Source: Memorial Sloan Kettering Integrative Medicine … Gotu Kola

Conditions

Frequently Asked Questions

What is Asiatic Pennywort Herb used for?

Asiatic Pennywort Herb is traditionally used to Clears Heat and promotes urination … used for Damp-Heat jaundice, painful urinary disorders, and summer-heat dysentery, Resolves toxicity and reduces swelling … applied internally or topically for abscesses, sores, shingles, and inflamed skin lesions, Promotes tissue regeneration and wound healing … valued for traumatic injury, chronic sores, burns, and delayed healing, Cools Blood and stops bleeding while also invigorating Blood … used for blood in the urine, epistaxis, bruising, and traumatic swelling. Research has investigated its effects on: Wound-healing and collagen support … asiaticoside increased collagen content, tensile strength, and epithelization in normal and delayed wound-healing models (PMID 10350364); Chronic venous insufficiency support … systematic review found improvement in microcirculatory parameters, edema, and related symptoms in controlled trials (PMID 23533507).

What are other names for Asiatic Pennywort Herb?

Asiatic Pennywort Herb is also known as Centella. In TCM: 积雪草 (Ji Xue Cao); Herba Centellae.

Is Asiatic Pennywort Herb safe during pregnancy?

The safety of Asiatic Pennywort Herb during pregnancy has not been established. Consult a qualified healthcare provider before use.

What are the contraindications for Asiatic Pennywort Herb?

Asiatic Pennywort Herb should not be used in: Spleen and Stomach deficiency-cold with loose stools or poor appetite; Cold-pattern dysmenorrhea or menstruation with marked Cold signs. Consult a qualified practitioner before use.

Does Asiatic Pennywort Herb interact with any medications?

Asiatic Pennywort Herb may interact with: CYP450 substrate drugs - In vitro gotu kola inhibits CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 and may alter intracellular concentrations of substrate drugs - (Moderate severity). Always inform your healthcare provider of any herbal supplements you are taking.