Asiatic Pennywort Herb

Chinese
积雪草
Pinyin
Ji Xue Cao
Latin
Herba Centellae

TCM Properties

Taste
bitter, acrid
Temperature
cold
Channels
Liver, Spleen, Kidney

Traditional Use

Primary Actions

  • Clears Heat and promotes urination — used for Damp-Heat jaundice, painful urinary disorders, and summer-heat dysentery
  • Resolves toxicity and reduces swelling — applied internally or topically for abscesses, sores, shingles, and inflamed skin lesions
  • Promotes tissue regeneration and wound healing — valued for traumatic injury, chronic sores, burns, and delayed healing
  • Cools Blood and stops bleeding while also invigorating Blood — used for blood in the urine, epistaxis, bruising, and traumatic swelling

Secondary Actions

  • Supports the Liver and Gallbladder in Damp-Heat patterns with jaundice or hepatitis
  • Fresh herb juice or poultice is a classic folk application for red eyes, sore throat, and hot swellings

Classical References

  • Shen Nong Ben Cao Jing (Divine Husbandman's Classic of Materia Medica) — records Ji Xue Cao as bitter and cold, indicated for great Heat, malignant sores, abscesses, spreading sores, red skin lesions, and fever.
  • Xin Xiu Ben Cao (Tang dynasty) — describes the coin-shaped leaves and recommends the pounded fresh herb applied topically for hot swellings and erysipelas.
  • Ben Cao Gang Mu (Compendium of Materia Medica, Li Shizhen, 1578) — notes that the expressed juice can be used for sudden red eyes and other acute Heat conditions.

Modern Research

Active Compounds

  • Asiaticoside
  • Madecassoside
  • Asiatic acid
  • Madecassic acid
  • Flavonoids and polyphenols

Studied Effects

  • Wound-healing and collagen support — asiaticoside increased collagen content, tensile strength, and epithelization in normal and delayed wound-healing models (PMID 10350364)
  • Chronic venous insufficiency support — systematic review found improvement in microcirculatory parameters, edema, and related symptoms in controlled trials (PMID 23533507)
  • Dermatologic scar and burn support — review literature highlights triterpenes for small wounds, hypertrophic scars, and burns (PMID 24399761)

PubMed References

Safety & Interactions

Contraindications

  • Spleen and Stomach deficiency-cold with loose stools or poor appetite
  • Cold-pattern dysmenorrhea or menstruation with marked Cold signs

Cautions

  • High doses or prolonged use may cause digestive upset or contribute to liver irritation in susceptible patients
  • Use with caution in patients with existing liver disease or when combining with other potentially hepatotoxic supplements

Drug Interactions

  • CYP450 substrate drugs — In vitro gotu kola inhibits CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 and may alter intracellular concentrations of substrate drugs (Moderate) Source: Memorial Sloan Kettering Integrative Medicine — Gotu Kola

Conditions