Asiatic Pennywort Herb (Luo De Da)

Chinese
落得打
Pinyin
Luo De Da
Latin
Herba Centellae

TCM Properties

Taste
bitter, acrid
Temperature
cold
Channels
Liver, Spleen, Kidney

Traditional Use

Primary Actions

  • Clears Heat and promotes urination — used for Damp-Heat jaundice, painful urinary disorders, and summer-heat dysentery
  • Resolves toxicity and reduces swelling — applied internally or topically for abscesses, sores, shingles, and inflamed skin lesions
  • Promotes tissue regeneration and wound healing — valued for traumatic injury, chronic sores, burns, and delayed healing
  • Cools Blood and stops bleeding while also invigorating Blood — used for blood in the urine, epistaxis, bruising, and traumatic swelling

Secondary Actions

  • Supports the Liver and Gallbladder in Damp-Heat patterns with jaundice or hepatitis
  • Fresh herb juice or poultice is a classic folk application for red eyes, sore throat, and hot swellings

Classical References

  • SYNONYM NOTE: Luo De Da (落得打) is an alternate Chinese name for the same whole-herb drug as Ji Xue Cao (积雪草, herb #114), both referring to Centella asiatica / Herba Centellae. The source XLSX imported them as separate entries; this file is retained separately, but the therapeutic, research, and safety profile is shared with herb #114.
  • AHPA Botanical Identity References Compendium lists both ji xue cao and luo-de-da as pinyin names for Centella asiatica aerial parts, confirming they are naming variants of the same botanical drug.
  • Traditional retail materia medica usage also records Luo De Da (落得打) as the market name for Centellae Herba in some Chinese-speaking dispensary contexts.

Modern Research

Active Compounds

  • Asiaticoside
  • Madecassoside
  • Asiatic acid
  • Madecassic acid
  • Flavonoids and polyphenols

Studied Effects

  • Wound-healing and collagen support — asiaticoside increased collagen content, tensile strength, and epithelization in normal and delayed wound-healing models (PMID 10350364)
  • Chronic venous insufficiency support — systematic review found improvement in microcirculatory parameters, edema, and related symptoms in controlled trials (PMID 23533507)
  • Dermatologic scar and burn support — review literature highlights triterpenes for small wounds, hypertrophic scars, and burns (PMID 24399761)

PubMed References

Safety & Interactions

Contraindications

  • Spleen and Stomach deficiency-cold with loose stools or poor appetite
  • Cold-pattern dysmenorrhea or menstruation with marked Cold signs

Cautions

  • High doses or prolonged use may cause digestive upset or contribute to liver irritation in susceptible patients
  • Use with caution in patients with existing liver disease or when combining with other potentially hepatotoxic supplements

Drug Interactions

  • CYP450 substrate drugs — In vitro gotu kola inhibits CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 and may alter intracellular concentrations of substrate drugs (Moderate) Source: Memorial Sloan Kettering Integrative Medicine — Gotu Kola

Conditions