Dutchmanspipe Vine — Safety & Interactions
Tian Xian Teng · Herba Aristolochiae
Contraindicated / High risk. Use only under practitioner supervision.
Contraindications
- Pregnancy
- Kidney disease or prior aristolochic acid nephropathy
- Any unsupervised internal use
- History of urothelial carcinoma or high renal-cancer risk
Cautions
- Tian Xian Teng belongs to the Aristolochia group, and aristolochic acid exposure has been linked to irreversible renal fibrosis, chronic kidney failure, and upper-tract urothelial carcinoma.
- Historical use in pregnancy-related edema should not be taken as a modern safety endorsement because the toxicology concerns are far more serious than the classical indication is important.
- MSK page not found - drug interaction data not available from Memorial Sloan Kettering integrative medicine database
Drug Interactions
| Drug Class / Substrate | Mechanism | Severity | Source |
|---|---|---|---|
| Nephrotoxic medications such as cisplatin, calcineurin inhibitors, or high-risk NSAID exposure - theoretical additive kidney injury risk | |||
Pregnancy
Not recommended during pregnancy. Consult a qualified practitioner before any use.
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before using herbal medicines, especially if you take prescription medications.