Forest Frog's Oviduct

Chinese
蛤蟆油
Pinyin
Ha Ma You
Latin
Oviductus Ranae

TCM Properties

Taste
sweet, salty
Temperature
neutral
Channels
Lung, Kidney

Traditional Use

Primary Actions

  • Tonifies the Kidney and supplements essence - Ha Ma You is used for chronic depletion, weakness after illness, and deficiency patterns marked by reduced reserve and poor recovery.
  • Moistens the Lung and nourishes Yin - traditional indications include dry consumptive cough, throat dryness, blood-streaked sputum, and deficiency-heat with night sweating.
  • Rebuilds depleted fluids and strength after prolonged illness or childbirth - it is valued as both a medicinal tonic and food-like restorative in Northeast Chinese practice.

Secondary Actions

  • Oviductus Ranae functions as both a classical animal medicine and a modern tonic food, so species authentication and hygienic sourcing matter more than with ordinary dried botanicals.
  • Its rich nourishing character makes it unsuitable in early exterior invasion or in damp-stagnation patterns with poor appetite and loose stool.

Classical References

  • TCM Wiki describes Ha Ma You as sweet, salty, and neutral, entering the Lung and Kidney to supplement Kidney essence while moistening the Lung and nourishing Yin.
  • Modern quality-control literature on Oviductus Ranae still repeats the traditional indication set of physical weakness, night sweats, dry cough, and Yin deficiency after illness.

Modern Research

Active Compounds

  • Proteins and bioactive peptides - the major nutrient and pharmacology-bearing fraction of Oviductus Ranae
  • Phospholipids and unsaturated fatty acids - relevant to tonic-food and endocrine-interest literature
  • Steroids and sterol-like constituents - part of the estrogen-like and ovarian-support discussion in modern studies
  • Amino acids, nucleosides, vitamins, and trace minerals - supportive nutritional constituents discussed in review literature

Studied Effects

  • A 2019 review summarized immunomodulatory, antioxidant, antifatigue, antiaging, antiosteoporotic, estrogen-like, and antitussive interests in Oviductus Ranae, while emphasizing its role as a tonic food more than as a routine prescription medicine (PMID 31281578).
  • A 2024 rat study reported that Oviductus Ranae promoted follicle growth, increased estradiol and progesterone levels, and upregulated PI3K/Akt-pathway signaling in ovarian tissue (PMID 39723099).
  • A toxicology study found no major acute, subacute, or genotoxic signal at tested experimental doses, but this remains preclinical and does not remove the need for careful sourcing and practitioner oversight (PMID 28341247).

PubMed References

Safety & Interactions

Contraindications

  • Early external pathogenic invasion
  • Poor appetite, food stagnation, or loose stool from dampness
  • Hormone-sensitive conditions without clinician oversight, given modern estrogen-like findings

Cautions

  • Authenticate species and source carefully; Oviductus Ranae is an animal-derived medicinal and adulteration or contamination risk is meaningful.
  • Modern work often describes estrogen-like, ovarian, or immune effects in preclinical settings rather than in large human trials.
  • Because it is a rich tonic, it can worsen damp accumulation or digestive stagnation in people without true deficiency.
  • MSK page not found - drug interaction data not available from Memorial Sloan Kettering integrative medicine database

Conditions